Microbial repellence properties of engineered spider silk coatings prevent biofilm formation of opportunistic bacterial strains

Abstract Bacterial infections are well recognised to be one of the most important current public health problems. Inhibiting adhesion microbes on biomaterials is approach for preventing inflammation. Coatings made recombinant spider silk proteins based consensus sequence Araneus diadematus dragline fibroin 4 have previously shown microbe-repellent properties. Concerning silicone implants, it has been further that coatings effective in lowering risk capsular fibrosis. Here, microbial repellence tests using four opportunistic infection-related strains revealed additional insights into properties silk-coated exemplarily surfaces. Graphic